Hello there,
I confirm that I have followed the r2 + python path to solve this. You do not need anything else. Just to confirm my analysis and because I was curious about debugging PE32 binaries with winedbg on my Debian workstation, I debugged the program using winedbg and it worked like a charm.
There are 3 well-known anti debugging techniques, so a couple of NOPs here and there should do the trick.
Cheers,